Downloads

http://www.treatoa.eu/wp-content/uploads/2013/08/download_featured_img_03.jpg

This software was funded by the Treat-OA project and is freely available for the analysis of the next generation sequence data.

  • VCF db

    Disclaimer: The software is provided as is, without warranty of any kind, express or implied, including but not limited to the warranties of merchantability, fitness for a particular purpose and non-infringement.
    In no event shall the authors, the participants of the Treat-OA Consortium nor their funders be liable for any claim, damages or other liability, whether in an action of contract, tort or otherwise, arising from, out of or in connection with the software or the use or other dealings in the software.

  • Click the link above to access the application

    The meta-analysis programme can be used for contrasting and combining results from different studies to identify patterns among study results, sources of disagreement among those results, or other interesting relationships that may come to light in the context of multiple studies.

  • Click the link above to access the application

Omics results in osteoarthritis. Hover over the images to use.

  • Click the link above to access the data

    All results for the hip OA GWAS meta analysis performed by TREAT-OA.

    Refers to this paper http://www.ncbi.nlm.nih.gov/pubmed/23989986

  • Click the link above to access the data

    Published GWAS hits for knee and hip OA as of  30 June 2012

  • Click the link above to access the data

    Gene Expression analyses of SNPs that are GWAS hits
    (i.e. TRANSCRIPTOMICS)

  • Click the link above to access the data

    Association between methylation levels and OA at probes mapping to genes that contain GWAS hits
    (i.e. EPIGENETICS)

  • Metabolomic Results

Deliverables



Atlas of mRNA expression patterns of the genes of interest as of 31/12/2008




Zebrafish gene expression patterns of genes identified in genetic screens


Morpholino efficiently downregulating expression of selected genes due month 18

test content


Plasmid expression constructs of chick homologues of human genes identified in WP1-4 due month 18


miRNA sequences able to interfere with the expression of selected genes due month 24


Reports